SC1

Summary

Gene Symbol: SC1
Description: activated leukocyte cell adhesion molecule
Alias: BEN, DM-GRASP, JC7, SC1, BEN glycoprotein, CD166 antigen, SC1 glycoprotein
Species: chicken

Top Publications

  1. doi Translation of the cell adhesion molecule ALCAM in axonal growth cones - regulation and functional importance
    Karsten Thelen
    Department of Developmental Neurobiology, Centre for Organismal Studies, University of Heidelberg, 69120 Heidelberg, Im Neuenheimer Feld 232, Germany
    J Cell Sci 125:1003-14. 2012
  2. ncbi Association of BEN glycoprotein expression with climbing fiber axonogenesis in the avian cerebellum
    O Pourquie
    Institut d Embryologie Cellulaire et Moleculaire du CNRS et du College de France, Nogent sur Marne
    J Neurosci 12:1548-57. 1992
  3. pmc BEN, a surface glycoprotein of the immunoglobulin superfamily, is expressed in a variety of developing systems
    O Pourquie
    Institut d Embryologie Cellulaire et Moleculaire, Nogent sur Marne, France
    Proc Natl Acad Sci U S A 89:5261-5. 1992
  4. ncbi DM-GRASP, a novel immunoglobulin superfamily axonal surface protein that supports neurite extension
    F R Burns
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104
    Neuron 7:209-20. 1991
  5. ncbi Molecular cloning and expression of a novel adhesion molecule, SC1
    H Tanaka
    Department of Pharmacology, Gunma University School of Medicine, Maebashi, Japan
    Neuron 7:535-45. 1991
  6. pmc Heterophilic interactions of DM-GRASP: GRASP-NgCAM interactions involved in neurite extension
    A P DeBernardo
    Department of Neuroscience, School of Medicine, University of Pennsylvania, Philidelphia 19104, USA
    J Cell Biol 133:657-66. 1996
  7. ncbi Expression and adhesive activity of SC1, an Ig superfamily cell adhesion molecule, in sporadic nephroblastomas of chicken
    Yasuhiro Tsukamoto
    Laboratory of Veterinary Anatomy, Graduate School of Biology and Environmental Sciences, Osaka Prefecture University, Japan
    Oncol Rep 15:137-41. 2006
  8. doi Ubiquitination and endocytosis of cell adhesion molecule DM-GRASP regulate its cell surface presence and affect its role for axon navigation
    Karsten Thelen
    Department of Developmental Neurobiology, University of Heidelberg, D 69120 Heidelberg, Germany
    J Biol Chem 283:32792-801. 2008

Scientific Experts

  • Yasuhiro Tsukamoto
  • Karsten Thelen
  • G Elisabeth Pollerberg
  • Marc Faber
  • Bettina Maier
  • Paulina Fischer
  • Christian Albrecht
  • Tanja Georg
  • Stefanie Bertuch
  • Pavol Zelina
  • A P DeBernardo
  • O Pourquie
  • S Chang
  • N M Le Douarin
  • H Tanaka
  • F R Burns
  • M E Hallonet
  • J P Le Caer
  • J Rossier
  • C Corbel
  • H S Phillips
  • A Agata
  • D L Shelton
  • T Matsui
  • J A Raper
  • A Lee
  • J Kamholz
  • K C McFarland
  • L Guy
  • B Kohr
  • M Tomura
  • I Kubota
  • S von Kannen

Detail Information

Publications8

  1. doi Translation of the cell adhesion molecule ALCAM in axonal growth cones - regulation and functional importance
    Karsten Thelen
    Department of Developmental Neurobiology, Centre for Organismal Studies, University of Heidelberg, 69120 Heidelberg, Im Neuenheimer Feld 232, Germany
    J Cell Sci 125:1003-14. 2012
    ..Taken together, these results show for the first time that translation of a cell adhesion molecule in growth cones, as well as the impact of this local translation on the behavior of axon and growth cone...
  2. ncbi Association of BEN glycoprotein expression with climbing fiber axonogenesis in the avian cerebellum
    O Pourquie
    Institut d Embryologie Cellulaire et Moleculaire du CNRS et du College de France, Nogent sur Marne
    J Neurosci 12:1548-57. 1992
    In a previous study, we have identified an avian 100 kDa membrane glycoprotein that we called BEN and demonstrated that it is transiently present in the CNS and PNS on the cell somas and axons of neurons that establish the peripheral ..
  3. pmc BEN, a surface glycoprotein of the immunoglobulin superfamily, is expressed in a variety of developing systems
    O Pourquie
    Institut d Embryologie Cellulaire et Moleculaire, Nogent sur Marne, France
    Proc Natl Acad Sci U S A 89:5261-5. 1992
    ..R., Von Kannen, S., Guy, L., Raper, J. A., Kamholz, J. & Chang, S. (1991) Neuron 7, 209-220] and SC1 [Tanaka, H., Matsui, T., Agata, A., Tomura, M., Kubota, I., Mcfarland, K. C., Kohr, B., Lee, A., Phillips, H. S...
  4. ncbi DM-GRASP, a novel immunoglobulin superfamily axonal surface protein that supports neurite extension
    F R Burns
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104
    Neuron 7:209-20. 1991
    ..Consequently we have named this protein DM-GRASP, since it is an immunoglobulin-like restricted axonal surface protein that is expressed in the dorsal funiculus and ventral midline of the chick spinal cord...
  5. ncbi Molecular cloning and expression of a novel adhesion molecule, SC1
    H Tanaka
    Department of Pharmacology, Gunma University School of Medicine, Maebashi, Japan
    Neuron 7:535-45. 1991
    b>SC1, an integral membrane glycoprotein of 100 kd, is uniquely and transiently expressed on spinal cord motoneurons early in development and appears in peripheral neurons and several other tissues during development...
  6. pmc Heterophilic interactions of DM-GRASP: GRASP-NgCAM interactions involved in neurite extension
    A P DeBernardo
    Department of Neuroscience, School of Medicine, University of Pennsylvania, Philidelphia 19104, USA
    J Cell Biol 133:657-66. 1996
    ..We present two possible models for the DM-GRASP-NgCAM association and a hypothesis for neural cell adhesion function that features the dimerization of cell adhesion molecules...
  7. ncbi Expression and adhesive activity of SC1, an Ig superfamily cell adhesion molecule, in sporadic nephroblastomas of chicken
    Yasuhiro Tsukamoto
    Laboratory of Veterinary Anatomy, Graduate School of Biology and Environmental Sciences, Osaka Prefecture University, Japan
    Oncol Rep 15:137-41. 2006
    b>SC1, an immunoglobulin superfamily cell adhesion molecule, is transiently expressed during avian embryogenesis by a variety of cell types...
  8. doi Ubiquitination and endocytosis of cell adhesion molecule DM-GRASP regulate its cell surface presence and affect its role for axon navigation
    Karsten Thelen
    Department of Developmental Neurobiology, University of Heidelberg, D 69120 Heidelberg, Germany
    J Biol Chem 283:32792-801. 2008
    ..Together, our data show that ubiquitination and endocytosis of DM-GRASP in concert regulate its cell surface concentration, which is crucial for its function in axon navigation...