Gene Symbol: PNPLA2
Description: patatin like phospholipase domain containing 2
Alias: ATGL, patatin-like phospholipase domain-containing protein 2, PNPLA2/ATGL, adipose triglyceride lipase
Species: chicken

Top Publications

  1. Serr J, Suh Y, Lee K. Regulation of adipose triglyceride lipase by fasting and refeeding in avian species. Poult Sci. 2009;88:2585-91 pubmed publisher
    ..b>Adipose triglyceride lipase (ATGL) is an adipose-specific enzyme that cleaves at the Sn-1 position of triglycerides, releasing ..
  2. Lee K, Shin J, Latshaw J, Suh Y, Serr J. Cloning of adipose triglyceride lipase complementary deoxyribonucleic acid in poultry and expression of adipose triglyceride lipase during development of adipose in chickens. Poult Sci. 2009;88:620-30 pubmed publisher
    ..An adipose triglyceride lipase (ATGL), recently identified in several species, has not been studied in avian species...
  3. Huang J, Zhang Y, Zhou Y, Wan X, Zhang J. Effects of epigallocatechin gallate on lipid metabolism and its underlying molecular mechanism in broiler chickens. J Anim Physiol Anim Nutr (Berl). 2015;99:719-27 pubmed publisher
    ..The results suggest that EGCG could alleviate fat deposition in broilers through inhibiting fat anabolism and stimulating lipid catabolism in broilers. ..
  4. Saarela J, Jung G, Hermann M, Nimpf J, Schneider W. The patatin-like lipase family in Gallus gallus. BMC Genomics. 2008;9:281 pubmed publisher
    ..Full-length cDNA sequences of galline PNPLA2/ATGL, PNPLA4, -7, -8, -9, and the activator protein CGI-58, as well as partial cDNA sequences of avian PNPLA1, -3, ..
  5. Nie Q, Fang M, Xie L, Shi J, Zhang X. cDNA cloning, characterization, and variation analysis of chicken adipose triglyceride lipase (ATGL) gene. Mol Cell Biochem. 2009;320:67-74 pubmed publisher
    b>Adipose triglyceride lipase (ATGL) is an important triglyceride-specific lipase that catalyzes the initial step in triglyceride hydrolysis...
  6. Nie Q, Hu Y, Xie L, Zhang C, Shen X, Zhang X. Identification and characterization of adipose triglyceride lipase (ATGL) gene in birds. Mol Biol Rep. 2010;37:3487-93 pubmed publisher
    b>Adipose triglyceride lipase (ATGL) is a triglyceride hydrolysis lipase and is generally related to lipid metabolism in animals...
  7. Nie Q, Fang M, Xie L, Shen X, Liu J, Luo Z, et al. Associations of ATGL gene polymorphisms with chicken growth and fat traits. J Appl Genet. 2010;51:185-91 pubmed publisher
    b>Adipose triglyceride lipase (ATGL) catalyses the initial step in triglyceride hydrolysis, so the ATGL gene is a candidate for growth and fat traits in chickens...