MUC2

Summary

Gene Symbol: MUC2
Description: mucin 2, oligomeric mucus/gel-forming
Alias: MUC5AC, mucin, mucin-2, mucin 2, intestinal/tracheal, mucin 5AC, oligomeric mucus/gel-forming
Species: chicken

Top Publications

  1. Lang T, Hansson G, Samuelsson T. An inventory of mucin genes in the chicken genome shows that the mucin domain of Muc13 is encoded by multiple exons and that ovomucin is part of a locus of related gel-forming mucins. BMC Genomics. 2006;7:197 pubmed
    ..Three transmembrane mucins (Muc4, Muc13, and Muc16) and four gel-forming mucins (Muc6, Muc2, Muc5ac, and Muc5b) were identified...
  2. Jiang Z, Applegate T, Lossie A. Cloning, annotation and developmental expression of the chicken intestinal MUC2 gene. PLoS ONE. 2013;8:e53781 pubmed publisher
    Intestinal mucin 2 (MUC2) encodes a heavily glycosylated, gel-forming mucin, which creates an important protective mucosal layer along the gastrointestinal tract in humans and other species...
  3. Zhang Q, Eicher S, Applegate T. Development of intestinal mucin 2, IgA, and polymeric Ig receptor expressions in broiler chickens and Pekin ducks. Poult Sci. 2015;94:172-80 pubmed publisher
    Intestinal mucin 2 (MUC2), a major gel-forming mucin, represents a primary barrier component of mucus layers and a target site for secretory IgA...
  4. Woodfint R, Chen P, Ahn J, Suh Y, Hwang S, Lee S, et al. Identification of the MUC2 Promoter as a Strong Promoter for Intestinal Gene Expression through Generation of Transgenic Quail Expressing GFP in Gut Epithelial Cells. Int J Mol Sci. 2017;18: pubmed publisher
    ..of gene expression in different tissues by analysis of a microarray database, the intestinal specificity of mucin 2 (MUC2) expression was identified in mice and humans, and further confirmed in chickens by RT-PCR (reverse ..
  5. de Barros Moreira Filho A, de Oliveira C, de Oliveira H, Campos D, Guerra R, Costa F, et al. High Incubation Temperature and Threonine Dietary Level Improve Ileum Response Against Post-Hatch Salmonella Enteritidis Inoculation in Broiler Chicks. PLoS ONE. 2015;10:e0131474 pubmed publisher
    ..inoculated with Salmonella Enteritidis, considering bacterial counts in the cecal contents, intestinal morphology, mucin and heat shock protein 70 gene expression, body weight and weight gain...