DNMT1

Summary

Gene Symbol: DNMT1
Description: DNA methyltransferase 1
Alias: DNA (cytosine-5)-methyltransferase 1, DNA (cytosine-5-)-methyltransferase 1, DNA MTase GgaI, DNA MeTase, DNA methyltransferase GgaI, MCMT, m.GgaI
Species: chicken
Products:     DNMT1

Top Publications

  1. Tajima S, Tsuda H, Wakabayashi N, Asano A, Mizuno S, Nishimori K. Isolation and expression of a chicken DNA methyltransferase cDNA. J Biochem. 1995;117:1050-7 pubmed
  2. Chuang L, Ian H, Koh T, Ng H, Xu G, Li B. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science. 1997;277:1996-2000 pubmed
    DNA-(cytosine-5) methyltransferase (MCMT) methylates newly replicated mammalian DNA, but the factors regulating this activity are unknown...
  3. Yu Y, Zhang H, Tian F, Zhang W, Fang H, Song J. An integrated epigenetic and genetic analysis of DNA methyltransferase genes (DNMTs) in tumor resistant and susceptible chicken lines. PLoS ONE. 2008;3:e2672 pubmed publisher
    ..modification of DNA methylation is catalyzed and maintained by the DNA methyltransferases (DNMT3a, DNMT3b and DNMT1)...
  4. Rengaraj D, Lee B, Lee S, Seo H, Han J. Expression patterns and miRNA regulation of DNA methyltransferases in chicken primordial germ cells. PLoS ONE. 2011;6:e19524 pubmed publisher
    ..28%). Our data highlight the structural conservation and conserved expression patterns of chicken DNMTs. The miRNAs investigated in this study may induce downregulation of gene expression in chicken PGCs and germ cells. ..