CXCR1

Summary

Gene Symbol: CXCR1
Description: C-X-C motif chemokine receptor 1
Alias: CXCR2, IL8RB, C-X-C chemokine receptor type 2, G-protein coupled receptor, chemokine (C-X-C motif) receptor 1, chemokine (C-X-C motif) receptor 2, interleukin 8 receptor, beta
Species: chicken

Top Publications

  1. Li Q, Lu S, Ye R, Martins Green M. Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. Gene. 2000;257:307-17 pubmed
    ..Using a human CXCR1 probe, we isolated several positive clones from a chicken genomic library...
  2. Li Q, Yao M, Dueck M, Feugate J, Parpura V, Martins Green M. cCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8). J Leukoc Biol. 2005;77:421-31 pubmed
    ..One noteworthy exception is the chemokine interleukin (IL)8/CXC ligand 8 and its specific receptor CXCR1, which are found in humans but are not found in the traditional model organisms, mice and rats...
  3. Poh T, Pease J, Young J, Bumstead N, Kaiser P. Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor. J Biol Chem. 2008;283:16408-15 pubmed publisher
    The original report of chicken CXCR1 (Li, Q. J., Lu, S., Ye, R. D., and Martins-Green, M. (2000) Gene (Amst.) 257, 307-317) described it as a single exon gene, with two isoforms (differing in their start codon)...