Research Topics

Genomes and Genes

Gene Symbol: CRY4

Description: cryptochrome 4

Alias: cryptochrome 4, cryptochrome-like protein

Species: chicken

Watari R, Yamaguchi C, Zemba W, Kubo Y, Okano K, Okano T. Light-dependent structural change of chicken retinal Cryptochrome4. J Biol Chem. 2012;287:42634-41 pubmed publisher

..In addition to the circadian clock genes Cry1 and Cry2, nonmammalian vertebrates have the Cry4 gene, the molecular function of which remains unknown...
Ozturk N, Selby C, Song S, Ye R, Tan C, Kao Y, et al. Comparative photochemistry of animal type 1 and type 4 cryptochromes. Biochemistry. 2009;48:8585-93 pubmed publisher

..degraded by a light-initiated reaction in Drosophila S2, zebrafish Z3, and human HEK293T cell lines, but zebrafish CRY4 (type 4) is not...
Mitsui H, Maeda T, Yamaguchi C, Tsuji Y, Watari R, Kubo Y, et al. Overexpression in yeast, photocycle, and in vitro structural change of an avian putative magnetoreceptor cryptochrome4. Biochemistry. 2015;54:1908-17 pubmed publisher

..Non-mammalian vertebrates have CRY4 in addition to the CRY1 and CRY2 circadian clock components...