CHRNA10

Summary

Gene Symbol: CHRNA10
Description: cholinergic receptor, nicotinic, alpha 10 (neuronal)
Alias: ALPHA 10 nAChR, neuronal acetylcholine receptor subunit alpha-10, NACHR alpha-10, alpha 10 subunit of nicotinic acetylcholine receptor, nicotinic acetylcholine receptor subunit alpha-10
Species: chicken

Top Publications

  1. Lipovsek M, Im G, Franchini L, Pisciottano F, Katz E, Fuchs P, et al. Phylogenetic differences in calcium permeability of the auditory hair cell cholinergic nicotinic receptor. Proc Natl Acad Sci U S A. 2012;109:4308-13 pubmed publisher
    ..In addition, they suggest that high Ca(2+) permeability of the ?9?10 cholinergic nicotinic receptor might have evolved together with other features that have given the mammalian ear an expanded high-frequency sensitivity...
  2. Boffi J, Marcovich I, Gill Thind J, Corradi J, Collins T, Lipovsek M, et al. Differential Contribution of Subunit Interfaces to α9α10 Nicotinic Acetylcholine Receptor Function. Mol Pharmacol. 2017;91:250-262 pubmed publisher
    ..We conclude that this asymmetry, which is supported by molecular docking studies, results from adaptive amino acid changes acquired only during the evolution of mammalian α10 subunits. ..