AMH

Summary

Gene Symbol: AMH
Description: anti-Mullerian hormone
Alias: muellerian-inhibiting factor
Species: chicken

Top Publications

  1. Oc n Grove O, Poole D, Johnson A. Bone morphogenetic protein 6 promotes FSH receptor and anti-Müllerian hormone mRNA expression in granulosa cells from hen prehierarchal follicles. Reproduction. 2012;143:825-33 pubmed publisher
    ..Interestingly, rhBMP6 also increases expression of anti-Müllerian hormone (AMH) mRNA in cultured 6-8?GC...
  2. Neeper M, Lowe R, Galuska S, Hofmann K, Smith R, Elbrecht A. Molecular cloning of an avian anti-Müllerian hormone homologue. Gene. 1996;176:203-9 pubmed
    Anti-Müllerian hormone (AMH) is responsible for regression of the Müllerian ducts in males during embryonic development...
  3. Oreal E, Pieau C, Mattei M, Josso N, Picard J, Carre Eusebe D, et al. Early expression of AMH in chicken embryonic gonads precedes testicular SOX9 expression. Dev Dyn. 1998;212:522-32 pubmed
    In mammals, anti-Müllerian hormone (AMH) is produced by Sertoli cells from the onset of testicular differentiation and by granulosa cells only after birth...
  4. Johnson P, Kent T, Urick M, Giles J. Expression and regulation of anti-mullerian hormone in an oviparous species, the hen. Biol Reprod. 2008;78:13-9 pubmed
    Anti-mullerian hormone (AMH) has a critical role in regression of the mullerian duct system during development in male mammalian and avian species and in regression of the right oviduct in female avian species...
  5. Johnson P, Kent T, Urick M, Trevino L, Giles J. Expression of anti-Mullerian hormone in hens selected for different ovulation rates. Reproduction. 2009;137:857-63 pubmed publisher
    In hens, the granulosa layer is the primary source of anti-Mullerian hormone (AMH), as it is in mammals. Small follicles express the greatest amount of Amh mRNA with less in the larger follicles...
  6. Lambeth L, Ayers K, Cutting A, Doran T, Sinclair A, Smith C. Anti-Müllerian Hormone Is Required for Chicken Embryonic Urogenital System Growth but Not Sexual Differentiation. Biol Reprod. 2015;93:138 pubmed publisher
    In mammals, the primary role of anti-Müllerian hormone (AMH) during development is the regression of Müllerian ducts in males. These structures otherwise develop into fallopian tubes, oviducts, and upper vagina, as in females...
  7. Lambeth L, Morris K, Ayers K, Wise T, O Neil T, Wilson S, et al. Overexpression of Anti-Müllerian Hormone Disrupts Gonadal Sex Differentiation, Blocks Sex Hormone Synthesis, and Supports Cell Autonomous Sex Development in the Chicken. Endocrinology. 2016;157:1258-75 pubmed publisher
    The primary role of Anti-Müllerian hormone (AMH) during mammalian development is the regression of Müllerian ducts in males...
  8. Eusèbe D, di Clemente N, Rey R, Pieau C, Vigier B, Josso N, et al. Cloning and expression of the chick anti-Müllerian hormone gene. J Biol Chem. 1996;271:4798-804 pubmed
    ..The chick anti-Müllerian hormone gene is expressed at high levels in Sertoli cells of the embryonic testes and in lower amounts in both ovaries, higher levels being reached on the left side after 10 days of incubation. ..
  9. Takada S, Mano H, Koopman P. Regulation of Amh during sex determination in chickens: Sox gene expression in male and female gonads. Cell Mol Life Sci. 2005;62:2140-6 pubmed
    ..development, the SOX9 transcription factor up-regulates expression of the gene encoding anti-Müllerian hormone (AMH), but in chickens, Sox9 gene expression reportedly occurs after the onset of Amh expression...

More Information

Publications10

  1. Takada S, Wada T, Kaneda R, Choi Y, Yamashita Y, Mano H. Evidence for activation of Amh gene expression by steroidogenic factor 1. Mech Dev. 2006;123:472-80 pubmed publisher
    The anti-Müllerian hormone gene (Amh) is responsible for regression in males of the Müllerian ducts. The molecular mechanism of regulation of chicken Amh expression is poorly understood...