Gene Symbol: ADORA2B
Description: adenosine A2b receptor
Alias: A2B-AR, adenosine receptor A2b, adenosine receptor 2b
- Worpenberg S, Burk O, Klempnauer K. The chicken adenosine receptor 2B gene is regulated by v-myb. Oncogene. 1997;15:213-21 pubmed..Our results provide the first evidence that v-Myb directly regulates a gene encoding a membrane receptor and establish a link between Myb function and adenosine receptor signaling. ..
- Braas D, Kattmann D, Miethe J, Klempnauer K. Analysis of DNase I-hypersensitive sites in the chromatin of the chicken adenosine receptor 2B gene reveals multiple cell-type-specific cis-regulatory elements. Gene. 2003;303:157-64 pubmed..Taken together, our data suggest that the expression of the A2B adenosine receptor gene in myelomonocytic cells is controlled by multiple cell type-specific cis-acting sequences located upstream and within the intron of the gene. ..
- Gundelach H, Braas D, Klempnauer K. The promoter regions of the Myb-regulated Adora2B and Mcm4 genes co-localize with origins of DNA replication. BMC Mol Biol. 2007;8:75 pubmed..We show that the promoter region of the chicken adenosine receptor 2B gene (Adora2B), a known Myb-target gene, acts as a DNA replication origin...
- Wojcik M, Zieleniak A, Mac Marcjanek K, Wozniak L, Cypryk K. The elevated gene expression level of the A(2B) adenosine receptor is associated with hyperglycemia in women with gestational diabetes mellitus. Diabetes Metab Res Rev. 2014;30:42-53 pubmed publisherAdenosine receptors denoted by A1 , A2A , A2B , and A3 and encoded by ADORA1, ADORA2A, ADORA2B, and ADORA3 genes, respectively, are adenosine-activated G-protein-coupled receptors that play an important role in obesity and type 2 ..