scn4a

Summary

Gene Symbol: scn4a
Description: sodium voltage-gated channel alpha subunit 4
Alias: scn4aa, sodium channel protein type 4 subunit alpha, Nav1.4a, voltage-gated sodium channel type IV alpha subunit Nav1.4a
Species: channel catfish

Top Publications

  1. Novak A, Jost M, Lu Y, Taylor A, Zakon H, Ribera A. Gene duplications and evolution of vertebrate voltage-gated sodium channels. J Mol Evol. 2006;63:208-21 pubmed publisher
    ..Interestingly, despite their different evolutionary histories, mRNA analyses demonstrated a conservation of expression patterns for SCNA orthologues in teleosts and tetrapods, suggesting functional conservation...
  2. Arnegard M, Zwickl D, Lu Y, Zakon H. Old gene duplication facilitates origin and diversification of an innovative communication system--twice. Proc Natl Acad Sci U S A. 2010;107:22172-7 pubmed publisher
    ..Earlier work suggested that a voltage-gated sodium channel gene (Scn4aa), which arose by whole-genome duplication, was neofunctionalized for expression in electric organ and subsequently ..

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