Gene Symbol: IL1B
Description: interleukin 1 beta
Alias: interleukin-1 beta, IL-1 beta, interleukin-beta
Species: cat
Products:     IL1B

Top Publications

  1. Cao W, Cheng L, Behar J, Biancani P, Harnett K. IL-1beta signaling in cat lower esophageal sphincter circular muscle. Am J Physiol Gastrointest Liver Physiol. 2006;291:G672-80 pubmed
    ..Both H(2)O(2) and PGE(2) production depend on sequential activation of p38 MAPK and cPLA(2). cPLA(2) activates NADPH oxidases, producing H(2)O(2), and may produce arachidonic acid, converted to PGE(2) via COX-2. ..
  2. Bhatt S, Bhatt R, Zalcman S, Siegel A. Role of IL-1 beta and 5-HT2 receptors in midbrain periaqueductal gray (PAG) in potentiating defensive rage behavior in cat. Brain Behav Immun. 2008;22:224-33 pubmed publisher
    ..The present study demonstrates that IL-beta in the dorsal PAG, similar to the medial hypothalamus, potentiates defensive rage behavior and is mediated through a 5-HT(2C) receptor mechanism...