Gene Symbol: ANPEP
Description: alanyl aminopeptidase, membrane
Alias: APN, aminopeptidase N, AP-M, AP-N, aminopeptidase M, fAPN, microsomal aminopeptidase
Species: cat
Products:     ANPEP

Top Publications

  1. Tresnan D, Levis R, Holmes K. Feline aminopeptidase N serves as a receptor for feline, canine, porcine, and human coronaviruses in serogroup I. J Virol. 1996;70:8669-74 pubmed
    ..I, human respiratory coronavirus HCV-229E and porcine transmissible gastroenteritis virus (TGEV), use aminopeptidase N (APN) as their cellular receptors...
  2. Miguel B, Pharr G, Wang C. The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review. Arch Virol. 2002;147:2047-56 pubmed
    Feline aminopeptidase N (fAPN) has been shown to serve as a receptor for feline, canine, porcine and human coronaviruses. Our objective was to determine if fAPN can serve as a receptor for infectious bronchitis virus (IBV)...
  3. Hegyi A, Kolb A. Characterization of determinants involved in the feline infectious peritonitis virus receptor function of feline aminopeptidase N. J Gen Virol. 1998;79 ( Pt 6):1387-91 pubmed
    Feline aminopeptidase N (fAPN) is a major cell surface receptor for feline infectious peritonitis virus (FIPV), transmissible gastroenteritis virus (TGEV), human coronavirus 229E (HCV 229E) and canine coronavirus (CCV)...
  4. Van Hamme E, Desmarets L, Dewerchin H, Nauwynck H. Intriguing interplay between feline infectious peritonitis virus and its receptors during entry in primary feline monocytes. Virus Res. 2011;160:32-9 pubmed publisher
    Two potential receptors have been described for the feline infectious peritonitis virus (FIPV): feline aminopeptidase N (fAPN) and feline dendritic cell-specific intercellular adhesion molecule grabbing non-integrin (fDC-SIGN)...
  5. Dye C, Temperton N, Siddell S. Type I feline coronavirus spike glycoprotein fails to recognize aminopeptidase N as a functional receptor on feline cell lines. J Gen Virol. 2007;88:1753-60 pubmed publisher
    ..It is generally accepted that feline aminopeptidase N can act as a receptor for the attachment and entry of type II strains, and it has been proposed that the same ..
  6. Kolb A, Hegyi A, Maile J, Heister A, Hagemann M, Siddell S. Molecular analysis of the coronavirus-receptor function of aminopeptidase N. Adv Exp Med Biol. 1998;440:61-7 pubmed
    b>Aminopeptidase N (APN) is a major cell surface for coronaviruses of the serogroup I...