xbx-1

Summary

Gene Symbol: xbx-1
Description: X-BoX promoter element regulated
Alias: X-BoX promoter element regulated
Species: Caenorhabditis elegans

Top Publications

  1. Schafer J, Haycraft C, Thomas J, Yoder B, Swoboda P. XBX-1 encodes a dynein light intermediate chain required for retrograde intraflagellar transport and cilia assembly in Caenorhabditis elegans. Mol Biol Cell. 2003;14:2057-70 pubmed
    ..Our results suggest that the DLIC protein XBX-1 functions together with the CHE-3 dynein in retrograde IFT, downstream of the complex A proteins. ..
  2. Burghoorn J, Dekkers M, Rademakers S, de Jong T, Willemsen R, Jansen G. Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2007;104:7157-62 pubmed
    ..We propose that DYF-5 plays a role in the undocking of kinesin II from IFT particles and in the docking of OSM-3 onto IFT particles. ..
  3. Bae Y, Lyman Gingerich J, Barr M, Knobel K. Identification of genes involved in the ciliary trafficking of C. elegans PKD-2. Dev Dyn. 2008;237:2021-9 pubmed publisher
    ..Identification of the remaining mutations will reveal novel molecular pathways required for ciliary receptor localization and provide further insight into mechanisms of ciliary signaling. ..
  4. Nguyen P, Liou W, Hall D, Leroux M. Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron. J Cell Sci. 2014;127:5317-30 pubmed publisher
    ..We propose that differential compartmentalization of signal transduction components by ciliary proteins is important for the functions of ciliated sensory neurons. ..
  5. Jensen V, Carter S, Sanders A, Li C, Kennedy J, Timbers T, et al. Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. PLoS Genet. 2016;12:e1006469 pubmed publisher