unc 9


Gene Symbol: unc 9
Description: Innexin;Innexin unc-9
Alias: Innexin;Innexin unc-9
Species: Caenorhabditis elegans

Top Publications

  1. Barnes T, Hekimi S. The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells. J Neurochem. 1997;69:2251-60 pubmed
    ..Finally, we speculate on the basis of the avermectin resistance and anesthetic response phenotypes. ..
  2. Starich T, Xu J, Skerrett I, Nicholson B, Shaw J. Interactions between innexins UNC-7 and UNC-9 mediate electrical synapse specificity in the Caenorhabditis elegans locomotory nervous system. Neural Dev. 2009;4:16 pubmed publisher
    ..elegans, and other factors must influence the determination of synaptic partners. ..
  3. Liu Q, Chen B, Gaier E, Joshi J, Wang Z. Low conductance gap junctions mediate specific electrical coupling in body-wall muscle cells of Caenorhabditis elegans. J Biol Chem. 2006;281:7881-9 pubmed
    ..These analyses provide a relatively detailed description of innexin-based gap junctions in a native tissue and suggest that innexin-based small conductance gap junctions can play an important role in processes such as locomotion. ..
  4. Chen B, Liu Q, Ge Q, Xie J, Wang Z. UNC-1 regulates gap junctions important to locomotion in C. elegans. Curr Biol. 2007;17:1334-9 pubmed
    ..Thus, in addition to the recently reported function of regulating mechanosensitive ion channels [5, 6], SLPs might have a novel function of regulating gap junctions. ..
  5. Sedensky M, Meneely P. Genetic analysis of halothane sensitivity in Caenorhabditis elegans. Science. 1987;236:952-4 pubmed
    ..Nematodes bearing the suppressor mutations alone have normal sensitivity to halothane. These results show that sensitivity to halothane can be altered by mutations in several different genes. ..
  6. Yeh E, Kawano T, Ng S, Fetter R, Hung W, Wang Y, et al. Caenorhabditis elegans innexins regulate active zone differentiation. J Neurosci. 2009;29:5207-17 pubmed publisher
    ..Our mosaic analyses, electron microscopy, as well as expression studies suggest a novel and likely nonjunctional role of specific innexins in active zone differentiation in addition to gap junction formations. ..
  7. Liu P, Chen B, Altun Z, Gross M, Shan A, Schuman B, et al. Six innexins contribute to electrical coupling of C. elegans body-wall muscle. PLoS ONE. 2013;8:e76877 pubmed publisher
    ..The results may serve as a solid foundation for further explorations of structural and functional properties of gap junctions in C. elegans body-wall muscle. ..