unc-50

Summary

Gene Symbol: unc-50
Description: Protein unc-50
Alias: Protein unc-50
Species: Caenorhabditis elegans

Top Publications

  1. Eimer S, Gottschalk A, Hengartner M, Horvitz H, Richmond J, Schafer W, et al. Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50. EMBO J. 2007;26:4313-23 pubmed
    ..These results suggest that, in addition to ER quality control, assembled AChRs are sorted within the Golgi system by a mechanism that controls the amount of cell-surface AChRs in a subtype-specific way. ..
  2. Lewis J, Wu C, Berg H, Levine J. The genetics of levamisole resistance in the nematode Caenorhabditis elegans. Genetics. 1980;95:905-28 pubmed
    ..elegans. And, as the most resistant class of mutants might lack pharmacologically functional acetyl-choline receptors (LEWIS et al. 1980), these mutants may also be of some neurobiological significance. ..
  3. Jospin M, Qi Y, Stawicki T, Boulin T, Schuske K, Horvitz H, et al. A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans. PLoS Biol. 2009;7:e1000265 pubmed publisher
    ..These data indicate that the ACR-2 receptor is important for the coordinated excitation and inhibition of body muscles underlying sinusoidal movement. ..