tsp-15

Summary

Gene Symbol: tsp-15
Description: Tetraspanin-15
Alias: Tetraspanin-15
Species: Caenorhabditis elegans

Top Publications

  1. Moribe H, Yochem J, Yamada H, Tabuse Y, Fujimoto T, Mekada E. Tetraspanin protein (TSP-15) is required for epidermal integrity in Caenorhabditis elegans. J Cell Sci. 2004;117:5209-20 pubmed
    ..These results indicate that TSP-15 functions in the maintenance of epithelial cell integrity. ..
  2. Moribe H, Konakawa R, Koga D, Ushiki T, Nakamura K, Mekada E. Tetraspanin is required for generation of reactive oxygen species by the dual oxidase system in Caenorhabditis elegans. PLoS Genet. 2012;8:e1002957 pubmed publisher
    ..Cell-fusion-based analysis suggested that association with TSP-15 at the cell surface is crucial for BLI-3 activation to release H(2)O(2). This study provides the first evidence for an essential role of tetraspanin in ROS generation. ..
  3. Xu Z, Luo J, Li Y, Ma L. The BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for iodide toxicity in Caenorhabditis elegans. G3 (Bethesda). 2014;5:195-203 pubmed publisher
    ..We propose that the BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for the toxic pleiotropic effects of excess iodide. ..