Gene Symbol: tlf-1
Description: TBP-Like Factor
Alias: TBP-Like Factor
Species: Caenorhabditis elegans

Top Publications

  1. Kaltenbach L, Horner M, Rothman J, Mango S. The TBP-like factor CeTLF is required to activate RNA polymerase II transcription during C. elegans embryogenesis. Mol Cell. 2000;6:705-13 pubmed
    ..Since CeTLF and CeTBP are expressed at comparable levels in the same cells, these findings suggest CeTLF performs a unique function in activating Pol II transcription distinct from that of CeTBP. ..
  2. Dantonel J, Quintin S, Lakatos L, Labouesse M, Tora L. TBP-like factor is required for embryonic RNA polymerase II transcription in C. elegans. Mol Cell. 2000;6:715-22 pubmed
    ..Thus, CeTLF may positively or negatively regulate Pol II transcription, depending on the developmental stage of the embryo. ..
  3. Walker A, Shi Y, Blackwell T. An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription. J Biol Chem. 2004;279:15339-47 pubmed
    ..Our findings imply that in metazoans TFIID may be of widespread importance for transcription and for expression of tissue-specific genes. ..