Research Topics

Genomes and Genes



Gene Symbol: smf-2
Description: NRAMP-like transporter smf-2
Alias: NRAMP-like transporter smf-2
Species: Caenorhabditis elegans

Top Publications

  1. Settivari R, Levora J, Nass R. The divalent metal transporter homologues SMF-1/2 mediate dopamine neuron sensitivity in caenorhabditis elegans models of manganism and parkinson disease. J Biol Chem. 2009;284:35758-68 pubmed publisher
    ..These studies describe a C. elegans model for manganism and show that DMT-1 homologues contribute to Mn(2+)- and PD-associated DA neuron vulnerability...
  2. Au C, Benedetto A, Anderson J, Labrousse A, Erikson K, Ewbank J, et al. SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans. PLoS ONE. 2009;4:e7792 pubmed publisher
    ..In sum, we unraveled a complex interplay of transcriptional and post-translational regulations of 3 DMT1-like transporters in two adjacent tissues, which regulate metal-content in C. elegans. ..