sam-4

Summary

Gene Symbol: sam-4
Description: hypothetical protein
Species: Caenorhabditis elegans

Top Publications

  1. Hansen M, Hsu A, Dillin A, Kenyon C. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet. 2005;1:119-28 pubmed
    ..Thus, our current view of the genetics of aging has probably not been distorted substantially by selection bias. ..
  2. Chiang W, Ching T, Lee H, Mousigian C, Hsu A. HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity. Cell. 2012;148:322-34 pubmed publisher
    ..Both the formation of DHIC and the phosphorylation of DDL-1 are controlled by IIS. Our findings point to DDL-1/2 as a link between IIS and the HSF-1 pathway. ..
  3. O Connell K, Leys C, White J. A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans. Genetics. 1998;149:1303-21 pubmed
    ..We conclude that this approach can be used to identify mutations that affect various aspects of the cell-division cycle. ..
  4. Song M, Liu Y, Anderson D, Jahng W, O Connell K. Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors. Dev Cell. 2011;20:563-71 pubmed publisher
    ..Together, our findings indicate that PP2A-SUR-6 promotes centriole assembly by protecting ZYG-1 and SAS-5 from degradation. ..
  5. Zheng Q, Ahlawat S, Schaefer A, Mahoney T, Koushika S, Nonet M. The vesicle protein SAM-4 regulates the processivity of synaptic vesicle transport. PLoS Genet. 2014;10:e1004644 pubmed publisher
    ..Our data support a model in which the SV protein SAM-4 regulates the processivity of SV transport. ..