rpt-4

Summary

Gene Symbol: rpt-4
Description: Probable 26S proteasome regulatory subunit 10B
Alias: Probable 26S proteasome regulatory subunit 10B
Species: Caenorhabditis elegans

Top Publications

  1. Song M, Liu Y, Anderson D, Jahng W, O Connell K. Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors. Dev Cell. 2011;20:563-71 pubmed publisher
    ..Together, our findings indicate that PP2A-SUR-6 promotes centriole assembly by protecting ZYG-1 and SAS-5 from degradation. ..
  2. Davy A, Bello P, Thierry Mieg N, Vaglio P, Hitti J, Doucette Stamm L, et al. A protein-protein interaction map of the Caenorhabditis elegans 26S proteasome. EMBO Rep. 2001;2:821-8 pubmed
  3. Takahashi M, Iwasaki H, Inoue H, Takahashi K. Reverse genetic analysis of the Caenorhabditis elegans 26S proteasome subunits by RNA interference. Biol Chem. 2002;383:1263-6 pubmed
    ..Ce-Rpn10 and Ce-Rpn12 are considered to compensate for the suppression of each other. ..
  4. Peel N, Dougherty M, Goeres J, Liu Y, O Connell K. The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels. J Cell Sci. 2012;125:3535-44 pubmed
    ..Co-depletion of LIN-23 and SEL-10 suggests these proteins function cooperatively. Because SEL-10 is the homolog of human FBW7, which is frequently mutated in cancer, our findings have implications for understanding tumorigenesis...
  5. Vora S, Phillips B. Centrosome-Associated Degradation Limits β-Catenin Inheritance by Daughter Cells after Asymmetric Division. Curr Biol. 2015;25:1005-16 pubmed publisher
    ..Based on our observations of centrosomal SYS-1 dynamics, we discuss the possibility that the centrosome may coordinate various cell-cycle-dependent processes by synchronizing mitosis and protein regulation. ..