rab-6.2

Summary

Gene Symbol: rab-6.2
Description: Ras-related protein Rab-6.2
Alias: Ras-related protein Rab-6.2
Species: Caenorhabditis elegans

Top Publications

  1. Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho M, et al. The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Mol Biol Cell. 2011;22:2564-78 pubmed publisher
    ..The GARP and COG tethering complexes may have overlapping functions for retrograde endosome-to-Golgi retrieval, since loss of both complexes leads to a synthetic lethal phenotype...
  2. Zhang D, Isack N, Glodowski D, Liu J, Chen C, Xu X, et al. RAB-6.2 and the retromer regulate glutamate receptor recycling through a retrograde pathway. J Cell Biol. 2012;196:85-101 pubmed publisher
    ..2 required LIN-10 activity. Our results demonstrate a novel role for RAB-6.2, its effector LIN-10, and the retromer complex in maintaining synaptic strength by recycling AMPARs along the retrograde transport pathway. ..
  3. Ailion M, Hannemann M, Dalton S, Pappas A, Watanabe S, Hegermann J, et al. Two Rab2 interactors regulate dense-core vesicle maturation. Neuron. 2014;82:167-80 pubmed publisher
    ..RUND-1 also interacts with the Rab2 GAP protein TBC-8 and the BAR domain protein RIC-19, a RAB-2 effector. In summary, a pathway of conserved proteins controls the maturation of dense-core vesicles at the trans-Golgi network...