Gene Symbol: ppfr-4
Description: Protein Phosphatase Four Regulatory subunit
Alias: Protein Phosphatase Four Regulatory subunit
Species: Caenorhabditis elegans

Top Publications

  1. Long X, Spycher C, Han Z, Rose A, Muller F, Avruch J. TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. Curr Biol. 2002;12:1448-61 pubmed
    ..The developmental arrest and intestinal phenotypes of CeTOR deficiency are due to an inhibition of global mRNA translation. Thus, TOR is a major upstream regulator of overall mRNA translation in C. elegans, as in yeast. ..
  2. Han X, Gomes J, Birmingham C, Pintard L, Sugimoto A, Mains P. The role of protein phosphatase 4 in regulating microtubule severing in the Caenorhabditis elegans embryo. Genetics. 2009;181:933-43 pubmed publisher
    ..The PP4 R1 regulatory subunit protein phosphatase four regulatory subunit 1 (ppfr-1) was identified in an RNA interference (RNAi) screen for suppressors of a mei-1(gf) ..
  3. Haag A, Gutierrez P, B├╝hler A, Walser M, Yang Q, Langouet M, et al. An in vivo EGF receptor localization screen in C. elegans Identifies the Ezrin homolog ERM-1 as a temporal regulator of signaling. PLoS Genet. 2014;10:e1004341 pubmed publisher
    ..The regulation of receptor localization thus serves to fine-tune the temporal activation of intracellular signaling pathways. ..