Gene Symbol: pod-2
Description: hypothetical protein
Species: Caenorhabditis elegans
Rappleye C, Tagawa A, Le Bot N, Ahringer J, Aroian R. Involvement of fatty acid pathways and cortical interaction of the pronuclear complex in Caenorhabditis elegans embryonic polarity. BMC Dev Biol. 2003;3:8 pubmed
Li Y, Na K, Lee H, Lee E, Paik Y. Contribution of sams-1 and pmt-1 to lipid homoeostasis in adult Caenorhabditis elegans. J Biochem. 2011;149:529-38 pubmed publisher
..Thus, both SAMS-1 and PMT-1 were shown to contribute to the homoeostasis of TG and PC levels in C. elegans, which would provide an important survival strategy under harsh environmental conditions. ..
Yuan Y, Kadiyala C, Ching T, Hakimi P, Saha S, Xu H, et al
. Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans. J Biol Chem. 2012;287:31414-26 pubmed publisher
..We conclude that an increase, not a decrease in fuel consumption, via an accelerated oxidation of fuels in the TCA cycle is involved in life span regulation; this mechanism may be conserved across phylogeny. ..
Lee K, Kniazeva M, Han M, Pujol N, Ewbank J. The fatty acid synthase fasn-1 acts upstream of WNK and Ste20/GCK-VI kinases to modulate antimicrobial peptide expression in C. elegans epidermis. Virulence. 2010;1:113-22 pubmed publisher
..The control of the antimicrobial peptide gene nlp?29 thus links different physiological processes, including fatty acid metabolism, osmoregulation, maintenance of epidermal integrity and the innate immune response to infection. ..
Zhang H, Abraham N, Khan L, Hall D, Fleming J, GOBEL V. Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis. Nat Cell Biol. 2011;13:1189-201 pubmed publisher
..Our findings identify glycosphingolipids, CGT products and obligate membrane lipids, as critical determinants of in vivo polarity and indicate that they sort new components to the expanding apical membrane...
Zhang Y, Zou X, Ding Y, Wang H, Wu X, Liang B. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. BMC Genomics. 2013;14:164 pubmed publisher
..This study provides the first systematic genomic insight into lipid metabolism in C. elegans, supporting the use of C. elegans as an increasingly prominent model in the study of metabolic diseases. ..