Gene Symbol: pgl-2
Description: P granule abnormality protein 2
Alias: P granule abnormality protein 2
Species: Caenorhabditis elegans

Top Publications

  1. Kawasaki I, Amiri A, Fan Y, Meyer N, Dunkelbarger S, Motohashi T, et al. The PGL family proteins associate with germ granules and function redundantly in Caenorhabditis elegans germline development. Genetics. 2004;167:645-61 pubmed
    ..Our findings demonstrate that both PGL-2 and PGL-3 are components of P granules, both interact with PGL-1, and at least PGL-3 functions redundantly with PGL-1 to ensure fertility in both sexes of C. elegans...
  2. Curran S, Wu X, Riedel C, Ruvkun G. A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. Nature. 2009;459:1079-84 pubmed publisher
    ..These results indicate that the acquisition of germline characteristics by the somatic cells of C. elegans mutants with increased longevity contributes to their increased health and survival. ..
  3. Kapelle W, Reinke V. C. elegans meg-1 and meg-2 differentially interact with nanos family members to either promote or inhibit germ cell proliferation and survival. Genesis. 2011;49:380-91 pubmed publisher
    ..Additionally, MEG activity is likely more directly involved in germ cell survival than previously thought. genesis 49:380-391, 2011. ..