Gene Symbol: pat-10
Description: Paralysed Arrest at Two-fold
Alias: Paralysed Arrest at Two-fold
Species: Caenorhabditis elegans
Kagawa H, Takuwa K, Sakube Y. Mutations and expressions of the tropomyosin gene and the troponin C gene of Caenorhabditis elegans. Cell Struct Funct. 1997;22:213-8 pubmed
..Both might affect the calcium binding or the retaining of the conformation for its function. Results presented here will be useful to understand the interaction site between the tropomyosin and troponin complex. ..
Williams B, Waterston R. Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations. J Cell Biol. 1994;124:475-90 pubmed
..Similar evidence suggests that one of the genes associated with mild effects on lattice assembly may code for tropomyosin. Many of the newly identified genes are likely to play critical roles in muscle development and function. ..
Ono K, Ono S. Tropomyosin and troponin are required for ovarian contraction in the Caenorhabditis elegans reproductive system. Mol Biol Cell. 2004;15:2782-93 pubmed
..These results strongly suggest that tropomyosin and troponin are the actin-linked regulators for contraction of ovarian muscle in the C. elegans reproductive system. ..
Xu X, Lee D, Shih H, Seo S, Ahn J, Lee M. Linking integrin to IP(3) signaling is important for ovulation in Caenorhabditis elegans. FEBS Lett. 2005;579:549-53 pubmed
..Sterility caused by RNAi of pat-3 and ECM molecules was suppressed by increased IP(3) signaling. Our data suggest that the cell-ECM interaction controls ovulation via IP(3) signaling. ..
Baird N, Douglas P, Simic M, Grant A, Moresco J, Wolff S, et al
. HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span. Science. 2014;346:360-3 pubmed publisher
Terami H, Williams B, Kitamura S, Sakube Y, Matsumoto S, Doi S, et al
. Genomic organization, expression, and analysis of the troponin C gene pat-10 of Caenorhabditis elegans. J Cell Biol. 1999;146:193-202 pubmed
..These combined biochemical and in vivo studies of mutant animals demonstrate that this troponin is essential for proper muscle function during development. ..
Ruksana R, Kuroda K, Terami H, Bando T, Kitaoka S, Takaya T, et al
. Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans. Genes Cells. 2005;10:261-76 pubmed
..Our results suggest the body wall genes have evolved following duplication of the pharynx gene and provide important data about gene duplication and functional differentiation of nematode troponin I isoforms. ..