nxf-1

Summary

Gene Symbol: nxf-1
Description: Nuclear RNA export factor 1;Nuclear eXport Factor
Alias: Nuclear RNA export factor 1;Nuclear eXport Factor
Species: Caenorhabditis elegans

Top Publications

  1. Tan W, Zolotukhin A, Bear J, Patenaude D, Felber B. The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p. RNA. 2000;6:1762-72 pubmed
    ..Therefore, despite differences in mRNA metabolism between these species, they utilize a conserved mRNA transport mechanism...
  2. Longman D, Johnstone I, Caceres J. The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA. 2003;9:881-91 pubmed
    ..Furthermore, no defects in mRNA export were observed upon simultaneous depletion of all three REF proteins. These results suggest the existence of multiple adaptor proteins that mediate mRNA export in C. elegans. ..
  3. Kawano T, Kataoka N, Dreyfuss G, Sakamoto H. Ce-Y14 and MAG-1, components of the exon-exon junction complex, are required for embryogenesis and germline sexual switching in Caenorhabditis elegans. Mech Dev. 2004;121:27-35 pubmed
    ..Our results demonstrate that the evolutionarily conserved interaction between two EJC components, Ce-Y14 and MAG-1, has critical developmental roles in C. elegans. ..
  4. Sheth U, Pitt J, Dennis S, Priess J. Perinuclear P granules are the principal sites of mRNA export in adult C. elegans germ cells. Development. 2010;137:1305-14 pubmed publisher
    ..However, we did not find evidence that P granules normally sequester aberrant mRNAs, or mRNAs targeted for destruction by the RNAi pathway. ..
  5. Zhang Z, Satterly N, Fontoura B, Chook Y. Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1. Mol Biol Cell. 2011;22:4657-68 pubmed publisher