Gene Symbol: nphp-2
Description: NePHronoPhthisis (human kidney disease) homolog
Alias: NePHronoPhthisis (human kidney disease) homolog
Species: Caenorhabditis elegans

Top Publications

  1. Warburton Pitt S, Silva M, Nguyen K, Hall D, Barr M. The nphp-2 and arl-13 genetic modules interact to regulate ciliogenesis and ciliary microtubule patterning in C. elegans. PLoS Genet. 2014;10:e1004866 pubmed publisher
    ..We conclude that the C. elegans InvC is distinct from the doublet region, and that components in these two regions interact to regulate ciliogenesis via cilia placement, ciliary microtubule ultrastructure, and protein localization. ..
  2. Nguyen P, Liou W, Hall D, Leroux M. Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron. J Cell Sci. 2014;127:5317-30 pubmed publisher
    ..We propose that differential compartmentalization of signal transduction components by ciliary proteins is important for the functions of ciliated sensory neurons. ..

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