nhl-1

Summary

Gene Symbol: nhl-1
Description: NHL (ring finger b-box coiled coil) domain containing;RING finger protein nhl-1
Alias: NHL (ring finger b-box coiled coil) domain containing;RING finger protein nhl-1
Species: Caenorhabditis elegans

Top Publications

  1. Gudgen M, Chandrasekaran A, Frazier T, Boyd L. Interactions within the ubiquitin pathway of Caenorhabditis elegans. Biochem Biophys Res Commun. 2004;325:479-86 pubmed
    ..Using NHL-1 as the E3 in the assays, ubiquitination was observed when both UBC-1 and UBC-13 were present but not with either alone. These data imply that some E2s require dimerization in order to function. ..
  2. Volovik Y, Moll L, Marques F, Maman M, Bejerano Sagie M, Cohen E. Differential regulation of the heat shock factor 1 and DAF-16 by neuronal nhl-1 in the nematode C. elegans. Cell Rep. 2014;9:2192-205 pubmed publisher
  3. Quevedo C, Kaplan D, Derry W. AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans. Curr Biol. 2007;17:286-92 pubmed
    ..Finally, we show that AKT-1 regulates apoptosis but not cell-cycle progression downstream of the HUS-1/MRT-2 branch of the DNA damage checkpoint. ..