nab-1

Summary

Gene Symbol: nab-1
Description: NeurABin
Alias: NeurABin
Species: Caenorhabditis elegans

Top Publications

  1. Sieburth D, Ch ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, et al. Systematic analysis of genes required for synapse structure and function. Nature. 2005;436:510-7 pubmed
    ..Twenty-four genes encoded proteins that were localized to presynaptic specializations. Loss-of-function mutations in 12 genes caused defects in presynaptic structure...
  2. Chia P, Patel M, Shen K. NAB-1 instructs synapse assembly by linking adhesion molecules and F-actin to active zone proteins. Nat Neurosci. 2012;15:234-42 pubmed publisher
    ..Next, the adaptor protein NAB-1 (neurabin) binds to F-actin and recruits active zone proteins SYD-1 and SYD-2 (liprin-?) by forming a tripartite complex...
  3. Hung W, Hwang C, Po M, Zhen M. Neuronal polarity is regulated by a direct interaction between a scaffolding protein, Neurabin, and a presynaptic SAD-1 kinase in Caenorhabditis elegans. Development. 2007;134:237-49 pubmed
    ..We identified a scaffolding protein, Neurabin (NAB-1), as a physiological binding partner of SAD-1...