Gene Symbol: miro-1
Description: Mitochondrial Rho GTPase 1
Alias: Mitochondrial Rho GTPase 1
Species: Caenorhabditis elegans

Top Publications

  1. Sieburth D, Ch ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, et al. Systematic analysis of genes required for synapse structure and function. Nature. 2005;436:510-7 pubmed
    ..Twenty-four genes encoded proteins that were localized to presynaptic specializations. Loss-of-function mutations in 12 genes caused defects in presynaptic structure...
  2. Ackema K, Hench J, Böckler S, Wang S, Sauder U, Mergentaler H, et al. The small GTPase Arf1 modulates mitochondrial morphology and function. EMBO J. 2014;33:2659-75 pubmed publisher
    ..Thus, Arf1 is involved in mitochondrial homeostasis and dynamics, independent of its role in vesicular traffic. ..
  3. Shen Y, Ng L, Low N, Hagen T, Gruber J, Inoue T. C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span. PLoS ONE. 2016;11:e0153233 pubmed publisher
    ..These results suggest that the reduction in the amount of mitochondria can affect the life span of an organism through activation of stress pathways. ..

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