Genomes and Genes
Gene Symbol: mig-10
Description: Abnormal cell migration protein 10
Alias: Abnormal cell migration protein 10
Species: Caenorhabditis elegans
- Ma L, Gao X, Luo J, Huang L, Teng Y, Horvitz H. The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. PLoS Genet. 2012;8:e1002827 pubmed publisher..Using a yeast two-hybrid screen, we isolated splicing factors as potential MFAP-1 interactors. Our studies indicate that C. elegans mfap-1 encodes a splicing factor that can affect alternative splicing. ..
- Wang Z, Chi Q, Sherwood D. MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans. Development. 2014;141:1342-53 pubmed publisher..These studies indicate that MIG-10 has distinct functions from UNC-40 signaling in cell invasion, and demonstrate that integrin coordinates invasion by localizing these molecules to the cell-basement membrane interface. ..
- Stavoe A, Col n Ramos D. Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton. J Cell Biol. 2012;197:75-88 pubmed publisher..Our data indicate that signaling modules known to organize the actin cytoskeleton during guidance can be co-opted to instruct synaptic vesicle clustering...
- Xu Y, Quinn C. MIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathways. PLoS Genet. 2012;8:e1003054 pubmed publisher..Together, these observations suggest that MIG-10 interacts with ABI-1 and WVE-1 to mediate the UNC-6 and SLT-1 guidance pathways...