mex-6

Summary

Gene Symbol: mex-6
Description: Zinc finger protein mex-6
Alias: Zinc finger protein mex-6
Species: Caenorhabditis elegans

Top Publications

  1. Huang N, Mootz D, Walhout A, Vidal M, Hunter C. MEX-3 interacting proteins link cell polarity to asymmetric gene expression in Caenorhabditis elegans. Development. 2002;129:747-59 pubmed
    ..We propose that MEX-6 and SPN-4 act with MEX-3 to translate the temporal and spatial information provided by the early acting par genes into the asymmetric expression of the cell fate determinant PAL-1. ..
  2. Cuenca A, Schetter A, Aceto D, Kemphues K, Seydoux G. Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases. Development. 2003;130:1255-65 pubmed
    ..These findings provide a model for how PAR and MEX proteins convert a transient asymmetry into a stably polarized axis. ..
  3. Nishi Y, Rogers E, Robertson S, Lin R. Polo kinases regulate C. elegans embryonic polarity via binding to DYRK2-primed MEX-5 and MEX-6. Development. 2008;135:687-97 pubmed publisher
    ..Our results provide a mechanism by which MEX-5 and MEX-6 function is temporally regulated during the crucial oocyte-to-embryo transition. ..
  4. Pagano J, Farley B, McCoig L, Ryder S. Molecular basis of RNA recognition by the embryonic polarity determinant MEX-5. J Biol Chem. 2007;282:8883-94 pubmed
    ..This residue is variable in nematode TZF proteins, but is invariant in other metazoans. Therefore, the divergence of TZF proteins and their critical role in early development is likely a nematode-specific adaptation. ..