mett-10

Summary

Gene Symbol: mett-10
Description: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
Alias: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
Species: Caenorhabditis elegans

Top Publications

  1. O Connell K, Leys C, White J. A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans. Genetics. 1998;149:1303-21 pubmed
    ..We conclude that this approach can be used to identify mutations that affect various aspects of the cell-division cycle. ..
  2. Dorsett M, Westlund B, Schedl T. METT-10, a putative methyltransferase, inhibits germ cell proliferative fate in Caenorhabditis elegans. Genetics. 2009;183:233-47 pubmed publisher
    ..The finding that METT-10 functions to inhibit germ-cell proliferative fate, despite promoting mitotic cell cycle progression of those germ cells that do proliferate, separates the specification of proliferative fate from its execution. ..
  3. Dorsett M, Schedl T. A role for dynein in the inhibition of germ cell proliferative fate. Mol Cell Biol. 2009;29:6128-39 pubmed publisher
    ..Our results add a new dimension to the processes controlled by the dynein motor complex, demonstrating that dynein can act as an antiproliferative factor. ..