Gene Symbol: mes-6
Description: Polycomb protein mes-6
Alias: Polycomb protein mes-6
Species: Caenorhabditis elegans
Sluder A, Lindblom T, Ruvkun G. The Caenorhabditis elegans orphan nuclear hormone receptor gene nhr-2 functions in early embryonic development. Dev Biol. 1997;184:303-19 pubmed
..nhr-2 does not correspond to known mutations mapped to the same genetic interval, and will provide an entry point for further study of a heretofore uncharacterized zygotic gene regulatory pathway. ..
Korf I, Fan Y, Strome S. The Polycomb group in Caenorhabditis elegans and maternal control of germline development. Development. 1998;125:2469-78 pubmed
..elegans than in Drosophila or vertebrates, and our studies suggest that their primary function is in controlling gene expression in the germline and ensuring the survival and proliferation of that tissue. ..
Xu L, Fong Y, Strome S. The Caenorhabditis elegans maternal-effect sterile proteins, MES-2, MES-3, and MES-6, are associated in a complex in embryos. Proc Natl Acad Sci U S A. 2001;98:5061-6 pubmed
..Our results suggest that the two C. elegans Polycomb group homologs (MES-2 and MES-6) associate with a novel partner (MES-3) to regulate germ-line development in C. elegans. ..
Dudley N, Labbé J, Goldstein B. Using RNA interference to identify genes required for RNA interference. Proc Natl Acad Sci U S A. 2002;99:4191-6 pubmed
..The finding that genes predicted to encode proteins that associate with chromatin are involved in RNAi in C. elegans raises the possibility that chromatin may play a role in RNAi in animals, as it does in plants. ..
Ross J, Zarkower D. Polycomb group regulation of Hox gene expression in C. elegans. Dev Cell. 2003;4:891-901 pubmed
..Thus, as in Drosophila, vertebrates, and plants, C. elegans PcG proteins regulate key developmental patterning genes to establish positional identity. ..
Bender L, Cao R, Zhang Y, Strome S. The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans. Curr Biol. 2004;14:1639-43 pubmed
..Our results contribute to understanding the composition and roles of E(Z)/MES-2 complexes across species...
Pires daSilva A, Sommer R. Finally, worm polycomb-like genes meet Hox regulation. Dev Cell. 2003;4:770-2 pubmed
..elegans. However, sequence comparison indicates that these genes may not be homologous to the fly Polycomb genes, suggesting that independent gene recruitment occurred during nematode evolution. ..