mat-2

Summary

Gene Symbol: mat-2
Description: Anaphase-promoting complex subunit 1
Alias: Anaphase-promoting complex subunit 1
Species: Caenorhabditis elegans

Top Publications

  1. Rappleye C, Tagawa A, Lyczak R, Bowerman B, Aroian R. The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell. 2002;2:195-206 pubmed
    ..We propose that the APC/separin pathway promotes close association of the centrosome with the cortex, which in turn excludes PAR-3 from the posterior pole early in a-p axis formation. ..
  2. Golden A, Sadler P, Wallenfang M, Schumacher J, Hamill D, Bates G, et al. Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans. J Cell Biol. 2000;151:1469-82 pubmed
    ..elegans CDC16 ortholog. ..
  3. Davis E, Wille L, Chestnut B, Sadler P, Shakes D, Golden A. Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I. Genetics. 2002;160:805-13 pubmed
    ..Further, chromosome segregation during meiosis I requires APC/C functions in addition to the release of sister chromatid cohesion. ..
  4. Yang H, Mains P, McNally F. Kinesin-1 mediates translocation of the meiotic spindle to the oocyte cortex through KCA-1, a novel cargo adapter. J Cell Biol. 2005;169:447-57 pubmed
    ..This study thus reveals two sequential mechanisms for translocating anastral spindles to the oocyte cortex. ..