Research Topics

Genomes and Genes

Gene Symbol: mai-2

Description: ATPase inhibitor mai-2, mitochondrial

Alias: ATPase inhibitor mai-2, mitochondrial

Species: Caenorhabditis elegans

Kaitna S, Pasierbek P, Jantsch M, Loidl J, Glotzer M. The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis. Curr Biol. 2002;12:798-812 pubmed

..Condensin mediates chromosome condensation during prophase, and condensin-independent pathways contribute to chromosome condensation during metaphase. ..
Ichikawa N, Ando C, Fumino M. Caenorhabditis elegans MAI-1 protein, which is similar to mitochondrial ATPase inhibitor (IF1), can inhibit yeast F0F1-ATPase but cannot be transported to yeast mitochondria. J Bioenerg Biomembr. 2006;38:93-9 pubmed

..MAI-2-GFP fusion protein was transported to yeast mitochondria, but MAI-1-GFP was not. These results indicate that the MAI-2 is (C. elegans) IF(1). MAI-1 seems to be a cytosolic protein and may regulate cytosolic ATPase(s). ..