Gene Symbol: magi-1
Description: MAGI (Membrane Associated Guanylate kinase Inverted) homolog
Alias: MAGI (Membrane Associated Guanylate kinase Inverted) homolog
Species: Caenorhabditis elegans

Top Publications

  1. Emtage L, Chang H, Tiver R, Rongo C. MAGI-1 modulates AMPA receptor synaptic localization and behavioral plasticity in response to prior experience. PLoS ONE. 2009;4:e4613 pubmed publisher
  2. Stetak A, Hörndli F, Maricq A, van den Heuvel S, Hajnal A. Neuron-specific regulation of associative learning and memory by MAGI-1 in C. elegans. PLoS ONE. 2009;4:e6019 pubmed publisher
    ..elegans are likely carried out by distinct subsets of interneurons. The synaptic scaffolding protein MAGI-1 plays a critical role in these processes in part by regulating the clustering of iGluRs at synapses. ..
  3. Lenfant N, Polanowska J, Bamps S, Omi S, Borg J, Reboul J. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. BMC Genomics. 2010;11:671 pubmed publisher
    ..The protein interactions from this publication have been submitted to the IMEx ( consortium through IntAct (PMID: 19850723) and assigned the identifier IM-14654]. ..
  4. Lynch A, Grana T, Cox Paulson E, Couthier A, Cameron M, Chin Sang I, et al. A genome-wide functional screen shows MAGI-1 is an L1CAM-dependent stabilizer of apical junctions in C. elegans. Curr Biol. 2012;22:1891-9 pubmed publisher
    ..Our results further suggest that MAGI-1 helps to partition and maintain a stable, spatially ordered apical junction during morphogenesis...
  5. Callaci S, Morrison K, Shao X, Schuh A, Wang Y, Yates J, et al. Phosphoregulation of the C. elegans cadherin-catenin complex. Biochem J. 2015;472:339-52 pubmed publisher
    ..Collectively, our findings support a model in which distinct phosphorylation events contribute to rapid CCC assembly and disassembly, both of which are essential for morphogenetic rearrangements during development. ..
  6. Stetak A, Hajnal A. The C. elegans MAGI-1 protein is a novel component of cell junctions that is required for junctional compartmentalization. Dev Biol. 2011;350:24-31 pubmed publisher
    ..Thus, the formation of stable junctions requires the proper distribution of the CCC and DAC adhesion protein complexes along the lateral plasma membrane. ..