lab-1

Summary

Gene Symbol: lab-1
Description: Long Arms of the Bivalent protein
Alias: Long Arms of the Bivalent protein
Species: Caenorhabditis elegans

Top Publications

  1. de Carvalho C, Zaaijer S, Smolikov S, Gu Y, Schumacher J, COLAIACOVO M. LAB-1 antagonizes the Aurora B kinase in C. elegans. Genes Dev. 2008;22:2869-85 pubmed publisher
    ..We propose that, in C. elegans, a LAB-1-mediated mechanism evolved to offset the challenges of providing protection against separase activity throughout a larger chromosome area. ..
  2. Tzur Y, Egydio de Carvalho C, Nadarajan S, Van Bostelen I, Gu Y, Chu D, et al. LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS Biol. 2012;10:e1001378 pubmed publisher