knl-3

Summary

Gene Symbol: knl-3
Description: Kinetochore NuLl
Alias: Kinetochore NuLl
Species: Caenorhabditis elegans

Top Publications

  1. Cheeseman I, Niessen S, Anderson S, Hyndman F, Yates J, Oegema K, et al. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 2004;18:2255-68 pubmed
    ..Thus, this protein network is a conserved constituent of the outer kinetochore, and the functions defined by our analysis in C. elegans are likely to be widely relevant. ..
  2. Cheeseman I, Chappie J, Wilson Kubalek E, Desai A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell. 2006;127:983-97 pubmed
    ..Based on these findings, we propose that the conserved KMN network constitutes the core microtubule-binding site of the kinetochore. ..
  3. Gassmann R, Essex A, Hu J, Maddox P, Motegi F, Sugimoto A, et al. A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Genes Dev. 2008;22:2385-99 pubmed publisher
  4. Dumont J, Oegema K, Desai A. A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis. Nat Cell Biol. 2010;12:894-901 pubmed publisher
    ..We suggest that separation is controlled by a meiosis-specific chromosomal domain to coordinate cohesin removal and chromosome segregation. ..