Gene Symbol: icd-1
Description: Transcription factor BTF3 homolog
Alias: Transcription factor BTF3 homolog
Species: Caenorhabditis elegans

Top Publications

  1. Bloss T, Witze E, Rothman J. Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans. Nature. 2003;424:1066-71 pubmed
    ..Human betaNAC is a caspase substrate that is rapidly eliminated in dying cells, suggesting that ICD-1 apoptosis-suppressing activity may be inactivated by caspases. ..
  2. Ciche T, Sternberg P. Postembryonic RNAi in Heterorhabditis bacteriophora: a nematode insect parasite and host for insect pathogenic symbionts. BMC Dev Biol. 2007;7:101 pubmed
    ..RNA interference is an excellent reverse genetic tool to study gene function in C. elegans, and it would be useful in H. bacteriophora to exploit the H. bacteriophora genome project, currently in progress...
  3. Arsenovic P, Maldonado A, Colleluori V, Bloss T. Depletion of the C. elegans NAC engages the unfolded protein response, resulting in increased chaperone expression and apoptosis. PLoS ONE. 2012;7:e44038 pubmed publisher
    ..elegans NAC in protein folding and localization during translation. Further, these findings confirm C. elegans as a valuable model for studying organismal and cell-type specific responses to misfolded protein stress. ..