Gene Symbol: hrp-1
Description: Heterogeneous nuclear ribonucleoprotein A1
Alias: Heterogeneous nuclear ribonucleoprotein A1
Species: Caenorhabditis elegans

Top Publications

  1. Hebeisen M, Drysdale J, Roy R. Suppressors of the cdc-25.1(gf)-associated intestinal hyperplasia reveal important maternal roles for prp-8 and a subset of splicing factors in C. elegans. RNA. 2008;14:2618-33 pubmed publisher
    ..Our findings suggest that in addition to its important regulatory function in the C. elegans germ line, prp-8(rr40) may provide further insight into the etiology of this splicing-associated human disorder. ..
  2. Longman D, Johnstone I, Caceres J. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. EMBO J. 2000;19:1625-37 pubmed
    ..RNAi with CeSRPK, an SR protein kinase, resulted in early embryonic lethality, suggesting an essential role for SR protein phosphorylation during development. ..
  3. Joeng K, Song E, Lee K, Lee J. Long lifespan in worms with long telomeric DNA. Nat Genet. 2004;36:607-11 pubmed
    ..Worms with long telomeres were more resistant to heat stress. Taken together, our results suggest that signaling may be initiated in postmitotic somatic cells by telomere length to regulate organismal lifespan. ..
  4. Zahreddine H, Zhang H, Diogon M, Nagamatsu Y, Labouesse M. CRT-1/calreticulin and the E3 ligase EEL-1/HUWE1 control hemidesmosome maturation in C. elegans development. Curr Biol. 2010;20:322-7 pubmed publisher
    ..Our findings should help understand how hemidesmosome dynamics are regulated in vertebrate systems. ..