Gene Symbol: him-14
Description: MutS protein homolog him-14
Alias: MutS protein homolog him-14
Species: Caenorhabditis elegans

Top Publications

  1. Zalevsky J, MacQueen A, Duffy J, Kemphues K, Villeneuve A. Crossing over during Caenorhabditis elegans meiosis requires a conserved MutS-based pathway that is partially dispensable in budding yeast. Genetics. 1999;153:1271-83 pubmed
    ..We discuss a model in which HIM-14 promotes crossing over by interfering with Holliday junction branch migration. ..
  2. Kemphues K, Kusch M, Wolf N. Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans. Genetics. 1988;120:977-86 pubmed
    ..If our interpretation is correct, we are near saturation for pure maternal genes in the region of LG II balanced by mnC1. We conclude that the number of pure maternal genes in C. elegans is small, being probably not much higher than 12. ..
  3. Labbé J, Pacquelet A, Marty T, Gotta M. A genomewide screen for suppressors of par-2 uncovers potential regulators of PAR protein-dependent cell polarity in Caenorhabditis elegans. Genetics. 2006;174:285-95 pubmed
    ..Taken together, our results identify conserved components that regulate PAR protein function and also suggest a role for NOS-3 in PAR protein-dependent cell polarity. ..
  4. Katz D, Edwards T, Reinke V, Kelly W. A C. elegans LSD1 demethylase contributes to germline immortality by reprogramming epigenetic memory. Cell. 2009;137:308-20 pubmed publisher
    ..Thus, our results provide direct mechanistic insights into the processes that are required for epigenetic reprogramming between generations. ..
  5. Kapelle W, Reinke V. C. elegans meg-1 and meg-2 differentially interact with nanos family members to either promote or inhibit germ cell proliferation and survival. Genesis. 2011;49:380-91 pubmed publisher
    ..Additionally, MEG activity is likely more directly involved in germ cell survival than previously thought. genesis 49:380-391, 2011. ..