hecd-1

Summary

Gene Symbol: hecd-1
Description: HECtD1 ubiquitin ligase homolog
Alias: HECtD1 ubiquitin ligase homolog
Species: Caenorhabditis elegans

Top Publications

  1. Basel Vanagaite L, Dallapiccola B, Ramirez Solis R, Segref A, Thiele H, Edwards A, et al. Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet. 2012;91:998-1010 pubmed publisher
    ..Our data reveal the pleiotropic effects of UBE3B deficiency and reinforce the physiological importance of ubiquitination in neuronal development and function in mammals. ..
  2. Chen Y, Greenwald I. hecd-1 modulates notch activity in Caenorhabditis elegans. G3 (Bethesda). 2014;5:353-9 pubmed publisher
  3. Zahreddine H, Zhang H, Diogon M, Nagamatsu Y, Labouesse M. CRT-1/calreticulin and the E3 ligase EEL-1/HUWE1 control hemidesmosome maturation in C. elegans development. Curr Biol. 2010;20:322-7 pubmed publisher
    ..Our findings should help understand how hemidesmosome dynamics are regulated in vertebrate systems. ..