Gene Symbol: gbf-1
Description: hypothetical protein
Species: Caenorhabditis elegans
Miyazawa Y, Takahashi A, Kobayashi A, Kaneyasu T, Fujii N, Takahashi H. GNOM-mediated vesicular trafficking plays an essential role in hydrotropism of Arabidopsis roots. Plant Physiol. 2009;149:835-40 pubmed publisher
..Furthermore, a weak gnom allele, gnomB/E, showed defect in hydrotropic response. These results indicate that GNOM-mediated vesicular trafficking plays an essential role in hydrotropism of seedling roots. ..
Winter J, HÃ¶pfner S, Korn K, Farnung B, Bradshaw C, Marsico G, et al
. Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity. Nat Cell Biol. 2012;14:666-76 pubmed publisher
..Our data suggest that PAR-5 acts as a regulatory hub for a polarity-maintaining network required for apicobasal asymmetry of F-actin and proper Rab11-RE positioning. ..
Ackema K, Sauder U, Solinger J, Spang A. The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans. PLoS ONE. 2013;8:e67076 pubmed publisher
..Our data suggest a role for GBF-1 in ER structure and endosomal traffic. ..
Ackema K, Hench J, BÃ¶ckler S, Wang S, Sauder U, Mergentaler H, et al
. The small GTPase Arf1 modulates mitochondrial morphology and function. EMBO J. 2014;33:2659-75 pubmed publisher
..Thus, Arf1 is involved in mitochondrial homeostasis and dynamics, independent of its role in vesicular traffic. ..