Gene Symbol: flp-22
Description: SPSAKWMRF-amide 3
Alias: SPSAKWMRF-amide 3
Species: Caenorhabditis elegans
Mertens I, Clinckspoor I, Janssen T, Nachman R, Schoofs L. FMRFamide related peptide ligands activate the Caenorhabditis elegans orphan GPCR Y59H11AL.1. Peptides. 2006;27:1291-6 pubmed
..Indeed, we found that the orphan receptor encoded by the Y59H11AL.1 gene is activated by several C. elegans neuropeptides, including SPMERSAMVRFamide. These peptides activate the receptor in a concentration-dependent way. ..
Grants J, Ying L, Yoda A, You C, Okano H, Sawa H, et al
. The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegans. Genetics. 2016;202:583-99 pubmed publisher
..Collectively, these data offer an explanation for CKM repression of EGFR signaling output and ectopic vulva formation and provide the first evidence of Mediator CKM-tail module subunit crosstalk in animals. ..
Mattout A, Pike B, Towbin B, Bank E, Gonzalez Sandoval A, Stadler M, et al
. An EDMD mutation in C. elegans lamin blocks muscle-specific gene relocation and compromises muscle integrity. Curr Biol. 2011;21:1603-14 pubmed publisher
..It has remained unresolved, however, whether the association of facultative heterochromatin with the nuclear periphery, or its release, has functional relevance for cell or tissue integrity...