Research Topics

Genomes and Genes

Gene Symbol: evl 20

Description: ADP-ribosylation factor-like protein 2

Alias: ADP-ribosylation factor-like protein 2

Species: Caenorhabditis elegans

Antoshechkin I, Han M. The C. elegans evl-20 gene is a homolog of the small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis. Dev Cell. 2002;2:579-91 pubmed

..Our data indicate that EVL-20 functions in the cytoplasm and at the plasma membrane to regulate cytoskeletal dynamics during cytokinesis and morphogenesis. ..
Li Y, Kelly W, Logsdon J, Schurko A, Harfe B, Hill Harfe K, et al. Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans. FASEB J. 2004;18:1834-50 pubmed

..elegans, at least three are required for embryogenesis. These data represent the first analysis of the role(s) of multiple members of this family in the development of a multicellular organism. ..