Gene Symbol: emb-27
Description: Cell division cycle protein 16 homolog
Alias: Cell division cycle protein 16 homolog
Species: Caenorhabditis elegans

Top Publications

  1. Sato K, Sato M, Audhya A, Oegema K, Schweinsberg P, Grant B. Dynamic regulation of caveolin-1 trafficking in the germ line and embryo of Caenorhabditis elegans. Mol Biol Cell. 2006;17:3085-94 pubmed
    ..Our results demonstrate that the distribution of CAV-1 is highly dynamic during development and provides new insights into the sorting mechanisms that regulate CAV-1 localization. ..
  2. Rappleye C, Tagawa A, Lyczak R, Bowerman B, Aroian R. The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell. 2002;2:195-206 pubmed
    ..We propose that the APC/separin pathway promotes close association of the centrosome with the cortex, which in turn excludes PAR-3 from the posterior pole early in a-p axis formation. ..
  3. Sato M, Grant B, Harada A, Sato K. Rab11 is required for synchronous secretion of chondroitin proteoglycans after fertilization in Caenorhabditis elegans. J Cell Sci. 2008;121:3177-86 pubmed publisher
  4. Kowalski J, Dube H, Touroutine D, Rush K, Goodwin P, Carozza M, et al. The Anaphase-Promoting Complex (APC) ubiquitin ligase regulates GABA transmission at the C. elegans neuromuscular junction. Mol Cell Neurosci. 2014;58:62-75 pubmed publisher
  5. Bezler A, GONCZY P. Mutual antagonism between the anaphase promoting complex and the spindle assembly checkpoint contributes to mitotic timing in Caenorhabditis elegans. Genetics. 2010;186:1271-83 pubmed publisher
    ..Taken together, our findings raise the possibility that the APC/C negatively regulates the SAC and, therefore, that the SAC and the APC/C have a mutual antagonistic relationship in C. elegans embryos. ..