elt 6


Gene Symbol: elt 6
Description: Erythroid-Like Transcription factor family
Alias: Erythroid-Like Transcription factor family
Species: Caenorhabditis elegans

Top Publications

  1. Koh K, Rothman J. ELT-5 and ELT-6 are required continuously to regulate epidermal seam cell differentiation and cell fusion in C. elegans. Development. 2001;128:2867-80 pubmed
    ..Collectively, these findings indicate that elt-5 and -6 function continuously throughout C. elegans development to regulate seam cell differentiation and cell fusion. ..
  2. Gorrepati L, Thompson K, Eisenmann D. C. elegans GATA factors EGL-18 and ELT-6 function downstream of Wnt signaling to maintain the progenitor fate during larval asymmetric divisions of the seam cells. Development. 2013;140:2093-102 pubmed publisher
  3. Tischler J, Lehner B, Chen N, Fraser A. Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution. Genome Biol. 2006;7:R69 pubmed
  4. Budovskaya Y, Wu K, Southworth L, Jiang M, Tedesco P, Johnson T, et al. An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans. Cell. 2008;134:291-303 pubmed publisher
    ..These results identify a transcriptional circuit that guides the rapid aging process in C. elegans and indicate that this circuit is driven by drift of developmental pathways rather than accumulation of damage. ..
  5. Liu W, Reece Hoyes J, Walhout A, Eisenmann D. Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6. BMC Dev Biol. 2014;14:17 pubmed publisher
    ..This work indicates that, as in other organisms, the regulation of Hox gene expression in C. elegans is complicated, redundant and robust. ..
  6. Koh K, Bernstein Y, Sundaram M. The nT1 translocation separates vulval regulatory elements from the egl-18 and elt-6 GATA factor genes. Dev Biol. 2004;267:252-63 pubmed
    ..By examining the fusion state and division patterns of the cells in the developing vulva of nT1 mutants, we demonstrate that egl-18/elt-6 prevent fusion and promote cell proliferation at multiple steps of vulval development. ..