egl 2


Gene Symbol: egl 2
Description: hypothetical protein
Species: Caenorhabditis elegans
Products:     egl 2

Top Publications

  1. Nguyen P, Liou W, Hall D, Leroux M. Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron. J Cell Sci. 2014;127:5317-30 pubmed publisher
    ..We propose that differential compartmentalization of signal transduction components by ciliary proteins is important for the functions of ciliated sensory neurons. ..
  2. Leboeuf B, Guo X, Garcia L. The effects of transient starvation persist through direct interactions between CaMKII and ether-a-go-go K+ channels in C. elegans males. Neuroscience. 2011;175:1-17 pubmed publisher
  3. LeBoeuf B, Garcia L. Cell excitability necessary for male mating behavior in Caenorhabditis elegans is coordinated by interactions between big current and ether-a-go-go family K(+) channels. Genetics. 2012;190:1025-41 pubmed publisher
    ..In conclusion, an interaction between BK and EAG family K(+) channels produces the muscle excitability levels that regulate the timing of spicule protraction and the success of male mating behavior. ..
  4. Weinshenker D, Wei A, Salkoff L, Thomas J. Block of an ether-a-go-go-like K(+) channel by imipramine rescues egl-2 excitation defects in Caenorhabditis elegans. J Neurosci. 1999;19:9831-40 pubmed
    ..Similar inhibition is observed with the mouse homolog MEAG, suggesting that inhibition of EAG-like channels may mediate some clinical side effects of this class of antidepressants. ..
  5. Trent C, Tsuing N, Horvitz H. Egg-laying defective mutants of the nematode Caenorhabditis elegans. Genetics. 1983;104:619-47 pubmed
    ..At least two of the egl mutants appear to be defective in the processing of environmental signals that modulate egg laying and may define new components of the neural circuitry that control egg laying. ..