egg-3

Summary

Gene Symbol: egg-3
Description: EGG sterile (unfertilizable)
Alias: EGG sterile (unfertilizable)
Species: Caenorhabditis elegans

Top Publications

  1. Maruyama R, Velarde N, Klancer R, Gordon S, Kadandale P, Parry J, et al. EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans. Curr Biol. 2007;17:1555-60 pubmed
    ..Therefore, EGG-3 plays a central role in egg activation by influencing polarized F-actin dynamics and the localization or activity of molecules that are directly involved in executing the egg-to-embryo transition. ..
  2. Stitzel M, Cheng K, Seydoux G. Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition. Curr Biol. 2007;17:1545-54 pubmed
    ..In C. elegans, degradation of the oocyte protein MEI-1 depends on MBK-2, a kinase that phosphorylates MEI-1 shortly after fertilization during the second meiotic division...
  3. Cheng K, Klancer R, Singson A, Seydoux G. Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition. Cell. 2009;139:560-72 pubmed publisher
    ..Our findings link cell-cycle progression to MBK-2/DYRK activation and the oocyte-to-embryo transition. ..